Top Immunotheropy Solution Companies-2022
Pharma Tech Outlook
OncoC4: Breaking Drug Resistance with Next-Gen Immunotherapy
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Top 10 Immunotheropy Solution Companies - 2022

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Modern healthcare professionals are exploring the depths of the technology facets of pharmaceutical solutions to open more avenues for immunotherapy innovations. The rise of immunotherapy is opening up treatment options for a growing number of previously incurable diseases and is completely transforming oncology care. Instilled with state-of-the-art technologies such as IoT, artificial intelligence (AI) and big data, finding new ways of identifying patients most likely to respond to specific immunotherapeutic approaches is now a primary focus. Moreover, the pursuit of exploring new ways of healthcare has led to a precise medication that can address a wide range of challenges related to cell therapy.

The Immunotherapy Drugs Market was valued at USD 164.68 billion in 2020 and is expected to reach USD 276.51 billion by 2026, registering a CAGR of 8.41% during the forecast period. The major factors attributing to this growth of the immunotherapy drugs market are the emergence of biosimilars, the rising adoption of targeted therapy over traditional therapy and a growing prevalence of chronic diseases and lifestyle disorders. In addition, the impact of COVID-19 on the immunotherapy drugs market is also positive because many companies are currently focused on developing immunotherapy-based drugs or vaccines for COVID-19. Moreover, the need for process efficiency and cost-effectiveness is engaging widespread automation efforts in cell therapy fields. Furthermore, factors such as growing research collaborations and emerging direct and indirect investments in research and development (R&D) by pharmaceutical and biotechnology companies are also supporting the market’s growth in the coming years.

At this juncture, there is a wide range of immunotherapy companies entering the market with a set of innovative immunotherapy solutions. To help leaders navigate through the list of immunotherapy solutions providers, Pharma Tech Outlook’s editorial board has narrowed down the top solutions providers in the landscape that are transforming immunotherapy treatments. Besides, the magazine also contains insights, best practices and advice for the aspiring CXOs. We present to you Pharma Tech Outlook’s “Top 10 Immunotherapy Solutions Providers - 2022.”

    Top Immunotheropy Solution Companies

    AbHelix leverages its proprietaryimmune sequencing technology platform with the vision to offer the required technologies to support immunotherapy research and development. ... read full profile
    Actinium Pharmaceuticals, Inc. is a clinical-stage biopharmaceutical company developing ARC’s or Antibody Radiation-Conjugates, which combine the targeting ability of antibodies with the cell killing ability of radiation. Actinium’s lead application for our ARC’s is targeted conditioning, which is intended to selectively kill patient’s cancer cells and certain immune cells prior to a BMT or Bone Marrow Transplant, CAR-T and other cell therapies. With our ARC approach, we seek to improve patient outcomes and access to these potentially curative treatments by eliminating or reducing the non-targeted chemotherapy that is used for conditioning in standard practice currently. Our lead product candidate, Iomab-B is being studied in the ongoing pivotal Phase 3 Study of Iomab-B in Elderly Relapsed or Refractory Acute Myeloid Leukemia (SIERRA) trial for BMT conditioning. Beyond Iomab-B, we are developing a multi-disease, multi-target pipeline of clinical-stage ARC’s targeting the antigens CD45 and CD33 for targeted conditioning and as a therapeutic either in combination with other therapeutic modalities or as a single agent for patients with a broad range of hematologic malignancies including AML or Acute Myeloid Leukemia, MDS or Myelodysplastic Syndrome MM or Multiple Myeloma. Underpinning our clinical programs is our proprietary AWE or Antibody Warhead Enabling technology platform. This is where our intellectual property portfolio of over 100 patents, know-how, collective research and expertise in the field are being leveraged to construct and study novel ARC’s and ARC combinations to bolster our pipeline and for strategic purposes. Our AWE technology platform is currently being utilized in a collaborative research partnership with Astellas Pharma, Inc. ... read full profile
    Coastar Therapeutics is a biotech company focusing on a novel delivery platform for repeated oncolytic virus dosing to fully utilize the potential of viral immunotherapy against cancer. Coastar's ELCV coating platform uses human cell lipid that contains self-identifying motifs to protect the virus from being neutralized by neutralizing antibodies and immune cells. This helps the OV fit for long-term storage and enables it to be shipped worldwide. The OV can be a truly off-the-shelf product compared to the rest of the offerings in the market, where they have to preserve the living cells and use the cell to carry oncolytic viruses. ... read full profile
    Based on its proven track record as a biopharma company and the popularity of its immunotherapeutic invention, Dendreon has launched a contract manufacturing services division to support cell therapy companies from clinical trial to the commercial launch of their product. We have been manufacturing our own cellular immunotherapy product, PROVENGE (sipuleucel-T)—the first-of-its-kind immunotherapy treatment for prostate cancer approved by FDA since 2010. Based on the experience and expertise we accumulated during the development and production of PROVENGE, we announced the launch of our contract manufacturing services division in 2021. Dendreon has extensive expertise in this domain and can bring its entire in-house infrastructure including manufacturing, patient logisitics, all the way to the final dosage infusion, all under one roof. ... read full profile
    KaliVir Immunotherapeutics was founded in 2019 to pioneer a unique and novel approach to cancer treatment that engages a virus’ natural ability to replicate in and kill cancer cells. KaliVir’s cutting-edge, next-generation oncolytic viral immunotherapy programs combine technologies developed in-house and licensed from the University of Pittsburgh’s world-class oncolytic virus and immunotherapy research programs. ... read full profile
    Notch Therapeutics provides a technology platform that unlocks the ability to generate T cells and other immune cells from renewable stem cell lines, simplifying manufacturing and offering the ability to produce immune cells at scale. The iPSC-derived cells are specifically engineered to address the underlying biology of complex disease systems. Based on their notch signaling research, Notch has built a platform that enables precision control of cell fate during the differentiation and expansion of stem cells in suspension bioreactors. The company is developing intellectual property around each of the six key elements of cell therapy: the nuclease, preventing graft-versus-host disease (GVHD) and graft rejection, binder and receptor architecture, solid tumor payload, and the kill switch. ... read full profile
    A clinical-stage biotech company focused on discovering new biologics for cancer treatment. ... read full profile
    Sumitomo Pharma Oncology is relentlessly committed to advancing purposeful science by transforming new discoveries into meaningful treatments for patients with cancer ... read full profile
    Founded in 2018, Teon Therapeutics is a clinical-stage bio-pharmaceutical start-up dedicated to improving the lives of cancer patients by developing a focused portfolio of small molecules that inhibit immunosuppressive and cancer-promoting signaling pathways in the tumor microenvironment (TME). Teon’s lead program TT-702 is an adenosine receptor antagonist and specifically targets the A2B receptor, which is over-expressed on various types of tumor cells, immune cells, and tumor-associated fibroblasts. ... read full profile
    Celsion Corporation
    Celsion Corporation is a fully integrated biopharmaceutical company focused on developing a portfolio of innovative cancer treatments, including directed chemotherapies, DNA-mediated immunotherapy, and RNA-based therapies. Our lead product candidate is ThermoDox®, a proprietary heat-activated liposomal encapsulation of doxorubicin, currently in a phase 3 trial combined with RFA for the treatment of hepatocellular carcinoma. Second in our pipeline is GEN-1, a DNA-mediated immunotherapy for the localized treatment of ovarian cancer. Celsion has 3 platform technologies providing the basis for the development of a range of therapeutics for difficult-to-treat forms of cancers. With these technologies we are working to develop and commercialize more efficient, effective, and targeted oncology therapies, maximizing efficacy while minimizing side effects common to cancer treatments.