Top Immunotherapy Solutions Companies-2023
Pharma Tech Outlook
Deka Biosciences: Made-to-Measure Cytokine Therapy
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Top 10 Immunotherapy Solutions Companies - 2023

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Since the invention of the first FDA-approved immune checkpoint inhibitor in 2011, the field of immunotherapy is growing exponentially. Multiple immunotherapeutic approaches dedicated to cancer vaccines, adoptive cell therapies, monoclonal antibodies, cytokine therapies, oncolytic viruses, and inhibitors targeting immune checkpoints are currently in development. Many of these approaches are already approved for specific cancer treatments while others are in their preclinical and clinical trial stages.

Further substantiating the success of immunotherapy are several providers in the medical research and pharmaceutical space that boost the efficacy of various strategies and eliminate the risk of therapy failures. Allison and Honjo’s discovery of T-cell immune checkpoints CTLA-4 and PD-1, which won the Nobel Prize in Physiology or Medicine was one of the successes that markedly propelled the cancer immunology field. In addition, several others are experimenting with the combination of cancer immunotherapy with functionalized nanosystems as a pivotal treatment strategy for multiple cancer types. Today, the expansion of new immuno-oncology (I-O) programs has increased the demand for optimum healthcare-dedicated predictive models that understand combination immunotherapy against a patient’s response and identify novel biomarkers.

This edition of Pharma Tech Outlook presents some of the most promising immunotherapy solution providers. The issue includes thought leadership articles from James Riddle, Vice President of research services & strategic consulting at Advarra. This edition also showcases innovative immunotherapy solutions from companies like Sorrento Therapeutics, a leading biopharmaceutical company delivering clinically meaningful therapies to address unmet medical needs.

    Top Immunotherapy Solutions Companies

    Deka Biosciences is a biotechnology company focused on generating next-generation targeted cytokine therapies to treat cancer and autoimmune diseases. It has developed a novel technology, termed DiakineTM that can be used to custom formulate therapies for a wide variety of cancer patients. ... read full profile
    MedOnect, Inc. is on a mission to develop innovative category-based products and medical devices that can reduce the severity of cancer diseases. ... read full profile
    Actinium Pharmaceuticals, Inc. is a clinical-stage biopharmaceutical company developing targeted radiotherapies to deliver cancer-killing radiation with cellular level precision to treat patients with high unmet needs. Actinium’s clinical pipeline is led by radiotherapies that are being applied to targeted conditioning, which is intended to selectively deplete a patient’s disease or cancer cells and certain immune cells ... read full profile
    Coastar Therapeutics is a pre-clinical biotech company developing biological payload delivery technologies for cancer immunotherapy and gene therapies. Their proprietary ENHEnSTM technology can be used to coat biological payloads with cell membranes, which help them evade recognition and clearance by the immune system and be successfully delivered to tumor or other disease sites. ... read full profile
    KaliVir Immunotherapeutics was founded in 2019 to pioneer a unique and novel approach to cancer treatment that engages a virus’ natural ability to replicate in and kill cancer cells. This modality is known as oncolytic viral immunotherapy. KaliVir’s cutting-edge, next generation oncolytic viral immunotherapy programs combine technologies developed in-house and licensed from University of Pittsburgh’s world-class oncolytic virus and immunotherapy research programs. ... read full profile
    Teon Therapeutics develops single-target small molecules designed to restore antitumor immunity and suppress cancer cell proliferation. The company’s created molecules combine treatments including metabolic checkpoint inhibitors and GPCR immune checkpoint inhibitors to unleash the full potential of immunotherapies by reinvigorating anti-cancer immunity, enabling healthcare professionals to improve long-term outcomes for more patients with cancer. ... read full profile
    Sorrento Therapeutics
    Sorrento Therapeutics works tirelessly to translate promising scientific discoveries into tangible treatments for patients. The company created a platform using a G MAB phage display library, which provides access to an enormous amount of antibody sequences, numbering in the tens of quadrillions. With this library, Sorrento Therapeutics can screen billions of antibodies in a matter of weeks to identify the ones that show promise in targeting specific diseases.
    AbbVie
    AbbVie is a pharmaceutical company with a strong exposure to immunology and oncology. AbbVie discovers and delivers innovative medicines and solutions that enhance people’s lives. The firm’s top drug, Humira, represents close to half of the company’s current profits. The company was spun off from Abbott in early 2013. The recent acquisition of Allergan adds several new drugs in aesthetics and women’s health.
    Amgen
    Amgen is committed to unlocking the potential of biology for patients suffering from serious illnesses by discovering, developing, manufacturing and delivering innovative human therapeutics. Amgen focuses on areas of high unmet medical need and leverages its expertise to strive for solutions that improve health outcomes and dramatically improve people’s lives.
    Novartis AG
    Novartis AG develops and manufactures healthcare products through two segments: Innovative Medicines and Sandoz. It generates the vast majority of its revenue from Innovative Medicines segment consisting global business franchises in oncology, ophthalmology, neuroscience, immunology, respiratory, cardiometabolic, and established medicines.